Modelling Human Disease in Rodents with CRISPR/Cas9 Genome Editing
Genetically modified rodents have brought major breakthroughs to biomedical research, but a conspicuous issue remains: why do the results discovered using these in vivo models sometimes fail to translate to human disease?
With new techniques such as CRISPR/Cas9-mediated genome editing, scientists now have access to an effective platform for generating a panel of mutations targeting a variety of backgrounds. This webinar discusses the promise CRISPR/Cas9 has for rodent studies along with strategies for developing accurate and predictive models to better understand and treat human disease.
- Guillaume Pavlovic, PhD, Department Head, Genetic Engineering and Model Validation, PHENOMIN-ICS